All patients should be carefully supervised regarding the development of mental modifications, depression and suicidal tendencies, or other such serious antisocial behavior. The patient should be cautioned not to change the prescribed dosage regimen and not to add any additional antiparkinson medications, including other carbidopa-levodopa preparations, without first consulting the physician. kopen sinemet geen voorschriften PRECAUTIONS General As with levodopa, periodic evaluations of hepatic, hematopoietic, cardiovascular, and renal function are recommended during extended therapy. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. To view our editorial policy, content sources and attributions please click here. Levodopa, an aromatic amino acid, is white, crystalline compound, slightly soluble in water, with molecular weight of 197. If this occurs, it may not work as well and may need to be thrown out and replaced.